Clinical Significance of homocysteine,coagulation function,platelet parameters and hemorheology detection in patients with cerebral infarction
10.3969/j.issn.1673-4130.2014.10.018
- VernacularTitle:脑梗死患者同型半胱氨酸、凝血功能、血小板参数和血液流变学指标检测的临床意义
- Author:
Dekui LI
;
Yue LIU
;
Qinghong ZHU
;
Ming′an ZHU
;
- Publication Type:Journal Article
- Keywords:
brain infarction;
cysteine;
hemorheology;
coagulation function;
platelet parameters
- From:
International Journal of Laboratory Medicine
2014;(10):1275-1276,1279
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of homocysteine(Hcy) ,coagulation function ,platelet parameters and he-morheology detection in patients with cerebral infarction .Methods 114 patients with cerebral infarction were served as cerebral in-farction group ,while 112 healthy people as control group .Their platelet parameters ,coagulation function ,Hcy and hemorheology were detected .Results Hcy ,Fibrinogen(Fib) and D-dimer(D-D) of patients in cerebral infarction group were higher than those in control group(P<0 .05) ,while the differences of prothrombin time(PT) ,activated partial thromboplastin time(APTT) and throm-bin time(TT) between the two groups showed no statistically significant (P> 0 .05) .In cerebral infarction group ,platelet count (PLT) of patients was lower ,and platelet distribution width(PDW) and mean platelet volume(MPV) were higher than those in the control group(P<0 .05) while plateletcrit(PCT) showed no statistically significant difference between the two groups (P<0 .05) . Whole blood viscosity ,plasma viscosity and hematocrit of patients in the cerebral infarction group were higher than those in the con-trol group(P< 0 .05) .Conclusion Hcy ,coagulation function ,platelet parameters and hemorheology detection have important significance for prediction and early diagnosis and treatment of cerebral infarction .
