Clinical analysis of 43 cases nasopharyngeal massive hemorrhage with nasopharyngeal carcinoma after radiotherapy
10.3760/cma.j.issn.1006-9801.2010.08.006
- VernacularTitle:鼻咽癌放疗后大出血43例
- Author:
Jun JIANG
;
Ning ZHANG
;
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal neoplasms;
Hemorrhage;
Radiotherapy,computer-assisted
- From:
Cancer Research and Clinic
2010;22(8):521-522,529
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors and preventive measures of nasopharyngeal massive hemorrhage in patients with nasopharyngeal carcinoma after radiotherapy. Methods Clinical data of 43 nasopharyngeal massive hemorrhage patients with nasopharyngeal carcinoma after radiotherapy were analyzed retrospectively. Results Thirty-nine cases(90.7 %) had abroad skull base invasion due to tumor, 36 cases (83.7%) received high dose of radiation, and 13 cases (30.2 %) were accompanied by diabetes. Conclusion Tumor location is the major factor for nasopharyngeal massive hemorrhage, while radiation dosage, fractionation patterns and diabetes are the secondary factors. The measures in cluding hyperfractionation, overall dose control and blood sugar regulation should be taken for the high risk patients. Prevention is more important than salvage.