Research Progress on PLGA Nanoparticles/Microspheres as DNA Carriers
- VernacularTitle:PLGA纳米/微球作为核酸载体的研究进展
- Author:
Gang WANG
;
Li PAN
;
Yong-Guang ZHANG
;
- Publication Type:Journal Article
- Keywords:
PLGA, DNA, Gene therapy, Vaccine adjuvant
- From:
Microbiology
2008;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Biodegradable PLGA [poly(lactide-co-glycolide acid)] have shown significant potential for sustained and targeted delivery of several pharmaceutical agents, including DNA. We reviewed the formulating approaches of PLGA nanoparticles/microspheres as DNA carriers and utilization for gene therapy and vaccine adjuvant.