A Review:the Molecular Mechanisms of InlA- and InlB- mediated Invasion of Listeria monocytogenes into Host Cell
- VernacularTitle:InlA和InlB介导单核细胞增生李斯特菌入侵宿主细胞分子机制的研究进展
- Author:
Ying-Ying FENG
;
Qiang ZHANG
;
Lan-Hong HUANG
;
Long-Juan QIN
;
Qin LUO
;
- Publication Type:Journal Article
- Keywords:
Listeria monocytogenes, Internalins, Host barriers, Molecular mechanisms
- From:
Microbiology
2008;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Gram-positive food-borne pathogen Listeria monocytogenes can invade non-phagocytic cells of the hosts by means of the special surface proteins and cause severe systemic infections. Internalins play a key role for Listeria monocytogenes in invading the non-phagocytic cells. In this study we will review and expand upon the recent advances in understanding the molecular mechanisms of InlA- and InlB- mediating the invasion of Listeria monocytogenes into host cells. This paper will also provide the theoretical base for pathogenetic mechanisms, precaution and therapy of food-borne pathogens.
