UV-B Irradiation Regulates Apoptosis in Yeast
- VernacularTitle:UV-B诱导的酵母凋亡现象及调节机制的作用
- Author:
Hua ZHAO
;
Dan WU
;
- Publication Type:Journal Article
- Keywords:
UV-B irradiation, Yeast cells, Apoptosis, Apoptotic regulation
- From:
Microbiology
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Mechanisms of UV-B-induced apoptotic regulation in yeast Saccharomyces cerevisiae were studied. The results showed that UV-B irradiation indeed inhibited the growth of yeast cells as well as induced extensive apoptosis during 96 h experiment period. However, survival of 96 h irradiated cells remained 10% while most control cells finally dead after re-growth under UV-B irradiation for 12 d. And by exposed to 0.01 mol/L or 0.1 mol/L H2O2 for 30 min, survival rate of 24 h irradiated cells were 3.0-fold or 3.2-fold than control, respectively. By to heat shock for 30 min or 60 min, survival rate of 24 h irradiated cells were 3.5-fold or 9.0-fold than control, respectively.
