Cyclic Diguanylate Signalling in Regulation of Bacterial Pathogenesis
- VernacularTitle:c-di-GMP信号途径对细菌致病性的调控作用
- Author:
Wen-Jing GUAN
;
Mao-Sen WU
;
Chen-Yang HE
;
- Publication Type:Journal Article
- Keywords:
Cyclic diguanylate, Virulence, Motility, Biofilm formation, Regulation
- From:
Microbiology
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Cyclic diguanylate (c-di-GMP) is a bacterial second messenger of growing recognition involved in the regulation of a number of complex physiological processes. In combinations to the related progress of Xanthomonas oryzae pv. oryzae, the causing agent of bacterial blight of rice in our lab, this review describes (1) the biosynthesis and hydrolysis of c-di-GMP and several mechanisms of regulation of c-di-GMP metabo-lism, (2) the contribution of c-di-GMP to regulating virulence, motility and biofilm formation, processes that affect pathogenesis of many bacteria, and (3) ways in which c-di-GMP may mediate these regulatory effects.
