Research Progress on the Microbial L-Arabinose Isomerase
- VernacularTitle:微生物来源的L-阿拉伯糖异构酶的研究进展及应用前景
- Author:
Li-Fang CHENG
;
Wan-Meng MU
;
Tao ZHANG
;
Bo JIANG
;
- Publication Type:Journal Article
- Keywords:
L-arabinose isomerase, D-tagatose, Structure and function, Enzyme properties, Genetic engi- neering
- From:
Microbiology
2008;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
L-arabinose isomerase (L-AI) can isomerize L-arabinose and D-galactose into L-ribulose and D-tagatose, respectively, which is currently the most effective biological catalyst for D-tagatose production. The crystal structure of L-AI has been solved recently and its gene has been cloned, sequenced and overex- pressed. L-AI improved by protein engineering will be the dominant enzyme for industrial production of D-tagatose. This paper reviewed researches on protein structure and function, properties and application in D-tagatose production of L-AI, and the long-term potential development of L-AI was prospected.
