Cyclodextrin and Its Derivatives as Non-viral Gene Vectors
- VernacularTitle:作为非病毒基因载体的环糊精及其衍生物
- Author:
Xiao ZHANG
;
Zhi-Zhang GUO
;
Lan HUANG
;
Jian-Shu LI
;
- Publication Type:Journal Article
- Keywords:
Cyclodextrin Cyclodextrin derivatives Polymer Nonviral gene vector Transfection efficiency
- From:
China Biotechnology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Cyclodextrin(CD) is gradually applied in the nonviral gene vector system,due to its biocompatibility and flexibility of tailing via structural modification,polymerization or supramolecular combination.The ideas and research progress of the CD,its low molecular derivatives,CD polymers and CD supramolecular combination in the field of norviral gene vectros were reviewed,and their "structure-safety-transfection efficiency" relationships were discussed.