Recent Progress on Plant Bioreactor Expressing Pharmaceutical Proteins
- VernacularTitle:植物生物反应器表达药用蛋白研究新进展
- Author:
Xiao-Chun DU
;
Zheng-Quan HE
;
Lei CHEN
;
Ye YANG
;
Wei YAO
;
- Publication Type:Journal Article
- Keywords:
Plant bioreactor Pharmaceutical proteins Progress
- From:
China Biotechnology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Plant bioreactor called mocular farming has enormous potential to produce recombinant protein infinitely. Products expressed in plants has nature physico-chemical property and bioactivity. Plant bioreactor could be an safe, economic and convenient production system which has been widely applied in industries and agriculture, especially in the life science and pharmaceutical industry. The application of recombinant transgenic plant in the production of vaccines, antibodies and pharmaceutical proteins has become a hot point in the plant genetic engineering both at home and broad. However, there are some limiting factors of application such as yield, downstream processing and so on. The advantages and research progress for the mocular farming of pharmaceutical proteins recent three years was discussed, focusing on the existing problems and new strategies in this area.