Impact of Age and Vascular Endothelial Function on Arterial Stiffness in Isolated Systolic Hypertersion
- VernacularTitle:单纯收缩期高血压病人年龄与血管内皮功能对大动脉僵硬度的影响
- Author:
Ya-Li WU
;
Meng-Jue LEI
;
Qiu-Ling LIU
;
Yan-Ping TU
;
Ai-Bin GONG
;
- Publication Type:Journal Article
- Keywords:
Isolated systolic hypertension;
Age;
Endothelial function;
Arterial stiffness
- From:
Chinese Journal of Hypertension
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of aging and vascular endothelial function on arterial stiff- ness in patients with isolated systolic hypertension.Methods Patients with isolated systolic hypertension (ISH,n=75)age-matched healthy subjects(n=30)and young healthy subjects(n=50)were submitted to deter- mination of aortic pulse wave velocity(baPWV)and vascular endothelial function evaluated by flow-mediated dila- tion(FMD).Results baPWV was progresively decreased(ISH:2459.2?436.8 vs elderly healthy:2097.2? 315.7 vs young healthy:1619.7?214.2 cm/s,P