Metabolic Syndrome Enhanced the Arteriosclerotic Development in Patients with Essential Hypertension
- VernacularTitle:原发性高血压患者合并代谢综合征加重血管内皮功能损害
- Author:
Hong-Wei WANG
;
Chao-Wu YANG
;
Xing-Yong JI
;
Jia-Gang WANG
;
- Publication Type:Journal Article
- Keywords:
Hypertension;
Metabolic diseases;
Carotid;
Arteriosclerosis
- From:
Chinese Journal of Hypertension
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of metabolic syndrome(MS)on the structure and function of artery in patients with essential hypertension(EH).Methods One hundred forty-eight patients with EH were classified as EH with MS(EH+MS)or EH alone and healthy subjects(n=30)as control.Carotid intima-media thickness(IMT),brachial artery flow-mediated vasodilation(FMD)and non-flow-mediated vasodilation(NMD)were measured by Dopple ultrasonography.Results Carotid IMT(EH+MS:1.0?0.3 vs EH:0.8?0.2 vs control: 0.5?0.1 mm)and hsCRP(EH+MS:0.9?0.4 vs EH:0.7?0.3 vs control:0.4?0.2 mg/L)were significantly higher in EH+MS patients than that in EH+nonMS patients and control subjects(P all
