Advance in Technique on the Development of Uncultured Microorganism
- VernacularTitle:开发未可培养微生物技术的研究进展
- Author:
Xiao-Yuan SUN
;
Ying LI
;
Ai-Dong QIAN
;
- Publication Type:Journal Article
- Keywords:
VBNC, Uncultured microorganism, Metagenomics, Genetic fingerprinting technical
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Viable but non-culturable state in bacterial cells as received uncultured microorganism has be- come the fundamental research issues in medical microbiology, epidemiology, general microbial ecology and sanitation quarantine since it was put forward in 1982. When in this state, bacterium are no longer able to grow and form colonies on conventional culture media, but maintain their patheogenicity, may become latent infection escaping detection to threaten enviroment and human security. With the development of modern molecular biology technique and metagenomics, it provide new research method and opportunity for uncul- tured microorganism in the environment. Recently, with the application of the metagenome technique, ge- netic fingerprinting technical etc, it becomes more and more popular. Simultaneously, along with this state become maturity in the laboratory. It provides a new research route for development and exploitation the uncultured microorganism.
