A Case of Pulmonary Alveolar Proteinosis that Improved with GM-CSF Inhalation Therapy.
- Author:
Bok Soon CHANG
1
;
Jungwon NOH
;
Chang Soo OK
;
Ga Yeon LEE
;
Seo Young SOHN
;
Sunha BAHNG
;
Man Pyo CHUNG
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. mp.chung@samsung.com
- Publication Type:Case Report
- Keywords:
Pulmonary alveolar proteinosis;
Bronchoalveolar lavage;
GM-CSF
- MeSH:
Aged;
Bronchoalveolar Lavage;
Colony-Stimulating Factors;
Granulocyte-Macrophage Colony-Stimulating Factor;
Humans;
Inhalation;
Lung;
Pulmonary Alveolar Proteinosis;
Respiratory Function Tests;
Respiratory Therapy;
Thorax
- From:Korean Journal of Medicine
2011;80(5):588-594
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pulmonary alveolar proteinosis (PAP) is a rare condition that is treated using whole lung lavage. A recent study suggested that granulocyte-macrophage colony stimulating factor (GM-CSF) plays roles in both the pathogenesis and treatment of PAP. We present a 69-year-old man with PAP who deteriorated despite bilateral whole lung lavage; that said, his symptoms, chest X-ray findings, and pulmonary function test improved after GM-CSF inhalation therapy over 12 months. GM-CSF therapy is an effective treatment modality for PAP.
