Progress in the Regulative Mechanism of Specific miRNA
- VernacularTitle:特异性miRNA调节机理研究进展
- Author:
Yu-Shu ZHENG
;
Pu ZHAO
;
Xing-You LIU
;
- Publication Type:Journal Article
- Keywords:
miRNA Specificity Regulative mechanism
- From:
China Biotechnology
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a newly identified class of non-protein-coding small RNAs that play important roles in multiple biological processes. Recent evidence indicates that the expression of many miRNAs is both temporally and spatially regulated by RNA editing, differential processing and tissue-specific enhancers, and the potential for ultimately designing molecular medicines based on the modulation of miRNAs seems good. A better understanding of the mechanism which regulates miRNAs is very helpful to reveal the pathogenesis of some diseases, discover novel molecular targets for treatment by interference, and develop an effective gene therapy. Therefore, the latest progress in the mechanism regulating miRNAs is summarized.
