Methodology for Aptamer Selection
- VernacularTitle:适配子筛选技术
- Author:
Hui-Qing ZHANG
;
Nian FANG
;
Kun-He ZHANG
;
- Publication Type:Journal Article
- Keywords:
Apatmer SELEX
- From:
China Biotechnology
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The methods for aptamer selection have been modified and developed in recent years. Selection efficiency has been increased due to the improvement in separation of bound and unbound nucleic acids; applicability of aptamers has been improved due to the development of primer-free SELEX and the utilization of short oligonucleotide library; more research requirements have been satisfied due to the functional modifications of aptamer selection methods. All the methodological advances enhance the potential value of aptamers in basic researches and clinical applications.
