Smoking Aggravates Large and Midio Arterial Stiffness in Patients with Essential Hypertensive
- VernacularTitle:吸烟加重高血压病患者大中动脉硬化
- Author:
Li-Qun DING
;
Ling JIANG
;
Jie FAN
;
- Publication Type:Journal Article
- Keywords:
Smoking;
Essential hypertension;
Big arterial stiffness
- From:
Chinese Journal of Hypertension
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of smoking on large arterial stiffness in patients with essential hypertensive.Methods The aortic,carotid and brachial arterial dimension,intimal-medial thickness were determined by vascular ultrasound technique.Wall cross sectional area and indices of compliance and distensibility were calculated in essential hypertensive patients with smoking(n=75) or without smoking(n=70).Results Hypertensive patients with smoking have increased wall intimal-medial thickness and wall cross sectional area in aortic,carotid and brachial arteries associated with decreased compliance and distensibility.After adjusting for the confounding effects of other variables including Age,BMI,HR,BP,PP,FPG,LDL-C and TG,covariance analysis show smoking remained as predisposed factors for vascular remodeling.Conclusion Smoking aggravates large arterial stiffness in essential hypertensive patients.
