Study of hCTGF Repair on Bone Injury
- VernacularTitle:采用质粒DNA研究人结缔组织生长因子(hCTGF)对骨损伤修复作用
- Author:
Ming SUN
;
Zhang-Long HE
;
Jing-Jing WANG
;
Shuai-Yao LU
;
Li-Chun WANG
;
Yuan ZHAO
;
Qi-Han LI
;
- Publication Type:Journal Article
- Keywords:
hCTGF Gene expression system Bone injury Bone healing
- From:
China Biotechnology
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Object: To study the proliferation of hCTGF on cells and its biological function on bone injury healing.Methods: The fibroblast with potential differentiation was transfected by eukaryotic gene delivery system and then transferred into the experimental animal model with bone fracture.The data were collected by molecular biological and clinical orthopedic technique detection analysis.Results: The results demonstrated an obvious proliferation of hCTGF on cells,suggesting that hCTGF have the biological activity of repairing bone injury via gene therapy.The results provide a new activity factor and treatment approach for bone injury in clinics.
