Application of cystatin C as an efficacious marker of renal function in kidney transplant recipients
- VernacularTitle:血清半胱氨酸蛋白酶抑制剂C在肾移植功能监测中的应用价值
- Author:
Sheng-Hua WANG
;
Xiao-Jing YANG
;
Xiong ZOU
;
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Cystatin C;
Allograft rejection;
Infection
- From:
Chinese Journal of Laboratory Medicine
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assss the clinical significance of Cystatin C(Cys C)as a marker of renal function in kidney transplant patients especially when infection or acute rejection occured.Methods Among 65 renal transplant recipients the concentrations of serum Cys C and serum creatinine(Scr)were determined before and one month after the transplantation,and also in the day and next day of occurrence of infection or rejection.Meanwhile,30 healthy persons and 30 infected patients without kidney transplantations were served as control.Results The concentrations of Cys C were nearly equal between healthy persons and the infected patients without kidney transplantations(P = 0.32).The level of serum Cys C and Scr dropped quickly in the first 3 days after transplantation(decreased by 69.2%,74.7%,75.8% for Cys C and 38.4%,74.5%,81.4% for Scr)(P
