Evaluation of the glomerular filtration function in type 2 diabetic patients
- VernacularTitle:对2型糖尿病患者肾小球滤过功能的评价
- Author:
Yan KONG
;
Jian-Mei YANG
;
Guo-Bin XU
;
Shu-Kui LI
;
Chun-Li ZHANG
;
Xiao-Hui GUO
;
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus type 2;
Cysteine proteinase inhibitors;
Creatinine
- From:
Chinese Journal of Laboratory Medicine
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of serum creatinine(Scr),creatinine clearance (Ccr),MDRD equation 7(MDRD 7),~(99)Tc~m-DTPA renal dynamic imaging(gGFR)and cystatin C in screening changed glomerular filtration function in type 2 diabetic patients.Methods The ~(99)Tc~m-Diethylene Triamine Pentaacetic Acid(~(99)Tc~m-DTPA)plasma clearance(rGFR)obtained with the dual plasma sampling method was used as a reference with which Scr,Ccr,MDRD 7,gGFR and Cystatin C were compared.Results Sixty of type 2 diabetic patients were selected,including 35 male and 25 female.The average age was(62.4?11.7)years and the average diabetic history was(10.66?9.35)years.Scr,Ccr, MDRD 7,gGFR were all correlated significantly with rGFR.Correlation coefficients were 0.675 for Ccr, -0.588 for Cystatin C,-0.500 for Scr,O.428 for MDRD 7,0.367 for gGFR(P values all
