Breeding of High Streptolydigin-Producing Strain by Complex Mutagenesis and Resistance Selection
- VernacularTitle:复合诱变和抗性筛选利迪链菌素高产菌株
- Author:
Wei-Huan GUO
;
Xiao-Bing LI
;
Ying-Jin YUAN
;
- Publication Type:Journal Article
- Keywords:
Streptomyces lydicus, Streptolydigin, Complex mutagenesis, Resistance selection
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
A high Streptolydigin-producing strain Streptomyces lydicus AS 4.2501-L8 with genetic stability was obtained from the original strain S. lydicus AS 4.2501-P28 by mutagenesis with UV and acridine orange, followed by resistance selection. Its yield of Streptolydigin was 177.0 ?g/mL, 96.2% higher than the original strain.
