Progress in the Research of Viral-encoded MiRNAs
- VernacularTitle:病毒编码的miRNAs研究进展
- Author:
Pu ZHAO
;
Yu-Shu ZHENG
;
Xing-You LIU
;
- Publication Type:Journal Article
- Keywords:
Virus miRNA Gene expression Regulator
- From:
China Biotechnology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs(miRNAs)are a class of small RNA molecules which play a pivotal role in the regulation of genes involved in diverse processes.Recently,many viral-encoded miRNAs have been discovered,which suggests that viruses also use this fundamental mode of gene regulation.Although the functions of most viral- encoded miRNAs are unknown,some of them are involved in evading CTL,mediating latent infection,apoptosis suppression,etc.Uncovering the role of viral miRNAs in the pathopoiesis offers an immense opportunity not only to develope effective antiviral therapies,but also to identifying novel molecular targets for developing antiviral reagents.Therefore,recent progress on vmiRNAs was reviewed.
