Diagnostic value of LUNX gene to marrow micrometastases of lung cancer
- VernacularTitle:术前检测骨髓中肺特异性X蛋白基因对肺癌微转移诊断的价值
- Author:
Xue-Yuan QI
;
Yu-Qing CHEN
;
Heng ZHANG
;
- Publication Type:Journal Article
- Keywords:
Reverse transcriptate-polymerase chain reaction;
Lung neoplasms;
Marrow micrometastases
- From:
Chinese Journal of Laboratory Medicine
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of LUNX gene to marrow micrometastases of lung cancer.Methods To detect LUNX mRNA of marrow samples of 51 patients of lung cancer,4 patients of breast cancer,6 patients of lymphadenoma,3 patients of liver cancer and 22 patients of benign disease by real-time RT-PCR.Results The positive detection rate and meso-copies of lung cancer were 58.8% (30/51) and 35copies/ml respectively.The positive detection rate and meso-copies of other diseases were all 0,The positive detection rate and meso-copies of lung cancer was significantly higher than that of patients with other diseases (x~2=11.12,U_c=3.7329,P
