CD127 and T Lymphocytes
- VernacularTitle:CD127与T淋巴细胞
- Author:
Chen-Ming SUN
;
Hai-Xia MA
;
Guang-Wei LIU
;
Yong ZHAO
;
- Publication Type:Journal Article
- Keywords:
CD127 IL7 T lymphocytes Immune regulatory
- From:
China Biotechnology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
CD127 is the interleukin7 receptor ?(IL7R?),it regulates the specific respond of T lymphocytes to IL7.CD127 plays an indispensable role in the development of thymocytes into T lymphocytes,the survival and homeostatic proliferation of memory T cells.There are only two phases of the life period of T cells that do not express CD127:immature CD4+8+double positive(DP)thymocytes and activated T cells.Recently,it was found that CD127 play an important role as the specific marker of memory T cells and regulator T cells.The role and mechanism of CD127 in the life period of T cells were discussed herein.
