Progress on the Study of Human Herpesvirus-8
- VernacularTitle:人类8型疱疹病毒的研究进展
- Author:
Xiaofei ZHOU
;
Lei YANG
;
Yan ZENG
;
- Publication Type:Journal Article
- Keywords:
Human herpesvirus-8 (HHV-8) Kaposi’s sarcoma Viral proteins
- From:
China Biotechnology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Human herpesvirus-8 (HHV-8) also referred to as Kaposi’s sarcoma-associated herpes-virus (KSHV),is a novel tumor causing virus,which is thought to be the etiologic agent of KS,and also is associated with primary effusion lymphoma(PEL) and multicentric castleman’s disease(MCD) HHV-8 encodes a number of viral proteins, including the proteins associated with HHV-8 latent infection and lytic infection,and the proteins unique to HHV-8,which are critical players in the development of KS and HHV-8-associated diseases. The proteins encoded by HHV-8 and association between HHV-8 and KS were reviewed.