To investigate plasma levels of free and total carnitine in patients undergoing hemodialysis or peritoneal dialysis
- VernacularTitle:血液透析和腹膜透析患者血浆游离和总肉毒碱水平的观察
- Author:
Li-Li JIAO
;
Fu-De ZHOU
;
Guo-Bin XU
;
Xue-Jing WANG
;
Jie DONG
;
Hai-Xia LI
;
Tie-An XIA
;
- Publication Type:Journal Article
- Keywords:
Carnitine;
Renal dialysis;
Peritoneal dialysis
- From:
Chinese Journal of Laboratory Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate plasma levels of total carnitine (TC) and free camitine (FC) in patients undergoing hemodialysis and peritoneal dialysis.Methods 200 cases of normal group came from physical examination in this hospital,all testing cases were the in-hospital patients in the department of nephropathy.TC and FC were determined by use of an enzymatic cycle assay on Hitachi 7170 automatic biochemical analyzer.Results In 200 cases of normal group,TC level was (56.52?9.61) ?mol/L,and FC was (46.60?8.23) ?mol/L.In 37 hemodialysis patients,TC and FC levels were (41.47?13.22) ?mol/L and (24.58?8.91)?mol/L before dialysis,a statistic difference was observed against the control group (P0.05).Conclusions Carnitine deficiency was seen in most patients undergoing hemodialysis and peritoneal dialysis.Furthermore,the deficiency status got worse along with the dialysis course in hemodialysis patients.Carnitine infusion can effectively improve the status of these patients.
