Clinical analysis of 31 patients with fungemia
- VernacularTitle:真菌血症31例临床分析
- Author:
Xiao-Bo MA
;
Xiao-Ju LII
;
Fei-Fei NIU
;
Xiao-Jing GUO
;
Xiaofu PAN
;
Yan-Yu GAO
;
- Publication Type:Journal Article
- Keywords:
Fungemia;
Pathogen;
Candida spp
- From:
Chinese Journal of Infection and Chemotherapy
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epiderniology of fungemia and provide evidence for clinical therapy.Methods A retro- spective survey was done with the 31 cases of fungemia in our hospital from August 2004 to November 2005.Results More than 80% of the patients suffered from two and more underlying diseases.Over a half of infections developed following placement of catheters.And 83.9% of the patients had a history of antimicrobial agents use before blood culture.The pathogens of 24 (77.4%) cases were associated with Candida spp.Only 3 strains were C.albicans.The mortality rate of candidemia was 45.8%.Different Candida species had different resistance rates to antifungal agents.Conclusions Fungemia patients often have serious underlying diseases.Most fungemia cases were candidemia caused by non-C.albicans.Some fungal pathogens are re- sistant to fluconazole and itraconazole.
