Analysis on the risk factors associated with fungal infection following operation of gastrointestinal neoplasm
- VernacularTitle:胃肠道肿瘤术后真菌感染危险因素分析
- Author:
Yu-Feng YAO
;
Zong-You CHEN
;
Peng SUN
;
Jian-Bin XIANG
;
Xiao-Dong GU
;
Duan CAI
;
- Publication Type:Journal Article
- Keywords:
Gastrointestinal neoplasm;
Fungal infection;
Risk factor
- From:
Chinese Journal of Infection and Chemotherapy
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relevant risk factors for fungal infection following operation of the gastrointestinal neo- plasm and offer supporting data for the prevention of fungal infection.Methods Medical records from 116 patients who under- went the operation of gastrointestinal neoplasm in the special group of this hospital from January 2006 to June 2006 were retro- spectively reviewed on the relevant risk factors by univariate and multivariate Logistic regression analysis.Results Of the 116 patients reviewed, 18 had fungal infection.Forty-six samples were positive for fungal pathogen.The most frequently isolated fungal strain was Candida albicans (15/20) and the most common infection site was gastrointestinal tract (14/18).Fungal in- fection after the operation of gastrointestinal neoplasm was significantly relevant with the duration of antibiotic use, duration of post-operative fasting, low serum albumin, high blood glucose and complication of bacterial infection.The duration of antibiotic use was a significantly independent risk factor.Conclusions Reasonable antibiotic use, nutritional support, early enteral nutri- tion and control of blood glucose should be taken into account after the operation of gastrointestinal neoplasm in order to prevent fungal infections.
