Exposure to Music and Noise During Pregnancy Influences Neurogenesis and Thickness in Motor and Somatosensory Cortex of Rat Pups.
- Author:
Chang Hee KIM
1
;
Sang Chul LEE
;
Je Wook SHIN
;
Kyung Jin CHUNG
;
Shin Ho LEE
;
Mal Soon SHIN
;
Sang Bin BAEK
;
Yun Hee SUNG
;
Chang Ju KIM
;
Khae Hawn KIM
Author Information
1. Department of Urology, Gachon University Gil Medical Center, Gachon University, Incheon, Korea. kimcho99@gilhospital.com
- Publication Type:Original Article
- Keywords:
Music;
Noise;
Neurogenesis;
Motor cortex;
Somatosensory cortex
- MeSH:
Animals;
Brain;
Fetus;
Humans;
Mothers;
Motor Cortex;
Music;
Neurogenesis;
Noise;
Parturition;
Pregnancy;
Rats;
Somatosensory Cortex
- From:International Neurourology Journal
2013;17(3):107-113
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Prenatal environmental conditions affect the development of the fetus. In the present study, we investigated the effects of exposure to music and noise during pregnancy on neurogenesis and thickness in the motor and somatosensory cortex of rat pups. METHODS: The pregnant rats in the music-applied group were exposed to 65 dB of comfortable music for 1 hour, once per day, from the 15th day of pregnancy until delivery. The pregnant rats in the noise-applied group were exposed to 95 dB of sound from a supersonic sound machine for 1 hour, once per day, from the 15th day of pregnancy until delivery. After birth, the offspring were left undisturbed together with their mother. The rat pups were sacrificed at 21 days after birth. RESULTS: Exposure to music during pregnancy increased neurogenesis in the motor and somatosensory cortex of rat pups. In contrast, rat pups exposed to noise during pregnancy showed decreased neurogenesis and thickness in the motor and somatosensory cortex. CONCLUSIONS: Our study suggests that music and noise during the developmental period are important factors influencing brain development and urogenital disorders.
