Study on the expression of PBMCs IP-10 mRNA and systemic lupus erythematosus
- VernacularTitle:系统性红斑狼疮患者外周血单个核细胞干扰素诱导的蛋白10mRNA表达的临床价值
- Author:
Zhong-Juan LIU
;
Yang GAO
;
Feng ZHANG
;
An-Ping NI
;
Jia-You LIN
;
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Reverse transcriptase polymerase-chain reaction
- From:
Chinese Journal of Laboratory Medicine
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relation between the expression of PBMCs IP-10 mRNA and systemic lupus erythematosus.Methods The expression of PBMCs IP-10 mRNA was investigated by RT-PCR semi quantitative method and samples from 46 patients with SLE,20 patients with RA,11 non-SLE patients with renal impairment and 20 healthy volunteers.Results The expression of PBMCs IP-10 mRNA in active SLE group was significantly higher than that in inactive group(P0.05).Serum levels of IP-10 were highly correlated with the expression levels of PBMCs IP-10 mRNA(r=0.897 1,P
