Measurement of the mRNA level of Polo-like kinase 1 in bronchoscopic bioptic specimens by realtime quantitative PCR
- VernacularTitle:肺癌活检组织中Polo样激酶-1mRNA水平检测的临床意义
- Author:
Ke-Jing YING
;
Fang-Chun SHAO
;
Bi-Yun YU
;
Jin-Min WU
;
Jia-Yi DING
;
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Ribonucleic acid;
Polymerase chain reaction;
Polo-like kinase 1
- From:
Chinese Journal of Laboratory Medicine
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05)and the TNM staging (P=0.55).A mild elevated compared other pathological classification was found in small cell lung cancer (0.191?0.275).Conclusions The results showed that RFQ-PCR was suitable for measurement of the mRNA level of PLKI in bronchoscopic bioptic specimens.This study suggest elevated expression of PLK1 might play a important role in development of lung cancer,so that PLK1 might be a potential tumor marker for Lung cancers.Advanced studies will be needed to clarify that PLKI mRNA level do not relate to TNM staging and pathological classification.
