A survey of nosocomial infections in ESRD patients undergoing blood purification
- VernacularTitle:终末期肾病血液净化住院患者医院感染分析
- Author:
Hui-Di ZHANG
;
Wei-Ming WANG
;
Jian WANG
;
Ping ZHU
;
Wen ZHANG
;
Nan CHEN
;
- Publication Type:Journal Article
- Keywords:
Hemodialysis;
Peritoneal dialysis;
Nosocomial infection;
Etiology;
End stage renal disease
- From:
Chinese Journal of Infection and Chemotherapy
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the morbidity and characteristic of nosocomial infections in end stage renal disease(ESRD) patients undergoing blood purification.Methods Medical records of ESRD patients undergoing blood purification from 2004 to 2005 were enrolled in this retrospective study of hospitalized cases.The clinical data of nosocomial infections in hemodialysis (HD)and peritoneal dialysis(PD)patients were analyzed separately.Results Nosocomial infection was identified in 76 of the 400 enrolled patients.In HD patients,pulmonary infection was the most common nosocomial infection(53.3%),most due to gram-negative microorganisms,followed by bloodstream(16.7%)and urinary tract infection(15%),most of both were due to gram-positive bacteria.Pulmonary infection was usually complicated.Bloodstream infection was associated with the duration of placement of central vein catheters.Asymptomatic bacteriuria accounted for most of the urinary tract infection.In PD patients, most infections were pulmonary infection(65.5%),mainly caused by fungal pathogens,followed by peritonitis(20.7%), mainly due to gram-positive bacteria.Certain proportion of infections in both groups was caused by multiple microorganisms or identified in multiple sites.Conclusions The prevalence of nosocomial infection is high in hospitalized patients undergoing blood purification.The infection is complicated in terms of pathogen and clinical picture.Pulmonary infection is the most common in- fection.The prevalence of fungal infection is increasing.Effective prevention and therapeutic measures should be applied more vigorously in ESRD patients.
