PFGE Genotyping of MRSA Outbreak in a Burn Unit
- VernacularTitle:烧伤病房MRSA医院感染暴发的PFGE分型研究
- Author:
Yu-Fen MENG
;
Li HAN
;
Gui-Zhi WU
;
Dong CHANG
;
Pei-Jun XU
;
- Publication Type:Journal Article
- Keywords:
MRSA, Pulsed field gel electrophoresis, Genotype
- From:
Microbiology
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
To explore the epidemiological character of Methicillin-resistant Stapkylococcus aureus (MRSA) by the phenotyping and genotyping motheds and to investgate the source, transmission, and the spread of nosocomial MRSA infection, consequently, reducing the nosocomial infection of MRSA. In this study, 19 MRSA strains were isolated from patients and environment in a hospital in two months. Patterns of resistantce against 16 antimicrobial agents and pulsed-field gel electrophoresis ( PFGE) of these strains were analyzed to find the relationship among those isolates Clustering analysis was made from the patterns. Some isolates with high homology was found in 19 MRSA, 11 of them belong to type A, and 8 of them belong to the same subtype A1. They were endemic in burn ward, oncological ward and ICU. In addition, 4 isolates were clustered into group B, all found in the same ward of burn unit Thus, our results indicated a outbreak of MRSA ( A type) in this hospital and the potential prevalence of MRSA (B type) , which might be mediated by health care stuff. It is essential to enhance the infection control implementation and to utilize the PFGE genotyping system for the real-time surveillance of MRSA.
