Influences of Bis(maltolato) oxovanadium in kidney morphology in spontaneously hypertensive rats
- VernacularTitle:联麦氧钒对自发性高血压大鼠肾脏形态学的影响
- Author:
SUN-JIE
;
Chun-Yan WANG
;
Lian-Wei YANG
;
- Publication Type:Journal Article
- Keywords:
Bis(maltolato) oxovanadium;
inbred spontaneously hypertension rats;
kidney/pathology
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Bis(maltolato) oxovanadium(BMOV) on renal structure of spontaneously hypertensive rats(SHRs) and its mechanism.Methods Thirty-six SHRs were divided into three groups at random: blank group,Nifedipine group and BMOV group.The light microscope and electron microscope were used to examine the pathologic changes of the kidney in rats.Results The rat glomerular mesangial expansion was found and the lumen of glomeruler capillary nearly closed in bland group,while in BMOV group the pathological changes mentioned above were unobvious.Conclusion BMOV may have protective effects on kidney in SHRs.
