Structure,Function and Evolution of Baculoviral Inhibitor of Apoptosis Protein Gene
- VernacularTitle:杆状病毒IAP基因的结构、功能及其进化
- Author:
Rui ZHANG
;
Qing YAO
;
Jian-Xin PENG
;
Hua-Zhu HONG
;
- Publication Type:Journal Article
- Keywords:
Baculovirus,IAP gene,Structure,Function,Evolution
- From:
Microbiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Baculoviral IAP(inhibitor of apoptosis protein) gene was identified firstly in IAP gene family.The structurcal feature of baculoviral IAP genes are characterized BIR and RING domain;Despite similar to P35 in antiapoptotic function,baculovrial IAP and P35 differ in structure and mechnism of action.Phylogenetic analysis of IAP genes and lots of evidence sppport the origin of this viral gene by capture of a host gene early in the evolution of Lepidoptera.
