Progress on the Study of Sex-specific Membrane Proteins in Mammalian Spermatozoa
- VernacularTitle:哺乳动物精子性别特异膜蛋白的研究进展
- Author:
Dong WANG
;
Zhen-Ling WANG
;
Jin-Hua CHENG
;
Hua-Bin ZHU
;
Hai-Sheng HAO
;
Yong-Hua LIU
;
- Publication Type:Journal Article
- Keywords:
Differential membrane protein Spermatozoa Gene expression
- From:
China Biotechnology
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The expression of specific genes in sex chromosomes is the basis of sex-specific membrane protein in mammalian spermatozoa. The gene expression products are shared among spermatozoa through intercellular bridges, however, the phenomena of male transmission-ratio distortion and sex ratio distortion proved that differential proteins exist between X and Y spermatozoa. In addition, the existence of sex-specific proteins was confirmed by the separation experiment of X/Y chromosome bearing spermatozoa and the detection result of sex specific proteins. At the same time, it was also confirmed that the difference of the sex-specific protein is weak . The advance of separation techniques as well as the integration and optimization among these techniques has made it possible to separate sex-specific membrane proteins in mammalian spermatozoa.
