The Advances and Application in the Expression of Heterologous Gene in Pichia pastoris
- VernacularTitle:毕赤酵母表达系统在外源基因表达中的研究进展及应用
- Author:
Wu-Kui ZHANG
;
Qing-Lin FAN
;
Li-Hua SONG
;
- Publication Type:Journal Article
- Keywords:
Pichia pastoris Heterologous gene Glycosylation
- From:
China Biotechnology
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Pichia pastoris is a new eukaryotic expression system with great potentials, has unexampled advantages in expressing the heterologous proteins and has gotten more and more wide application. The following aspects were described in detail: the advantages of Pichia pastoris in the expression of heterologous genes, the mechanism of the heterologous gene integrations, the glycosylation of the expressed protein and the modification of the post-translated protein.