The Screening and Study of Arctic Marine Psychrophilic Bacterial for Anti-tumor and Antibacterial Activity
- VernacularTitle:一株抗小鼠乳腺癌和一株有抑菌活性的北极细菌的初步研究
- Author:
Hong-Qiang SHANG
;
Tian-Jiao ZHU
;
Qian-Qun GU
;
Wei-Ming ZHU
;
Hua-Shi GUAN
;
- Publication Type:Journal Article
- Keywords:
Arctic, Psychrophilic bacteria, Anti-tumor activity, Antibacte rial activity
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
In this study, 101 strains of bacteria were isolated from arct ic water and sediment samples. The methanol extracts of the fermented broth prod uced by these strains were screened in vitro for anti-tumor activity on mou se tsFT210 cells using the method of flow cytometry, and screened for antibacter ial activity by the method of paper disk diffusion. The result showed that one strain exhibited anti-tumor activity and eight strains had antibacterial activ ity. The stability of the antibacterial components produced by strain AR084 an d its optimum medium were also studied. The research indicated that arctic bac teria had potential application in pharmaceutics.
