A Clinical Trial of Paroxetine and Psychotherapy in Patients with Poststroke Depression and Anxiety
- VernacularTitle:帕罗西汀并心理干预治疗卒中后抑郁和焦虑共病者81例临床观察
- Author:
Xin WANG
;
Yan HE
;
Chun-Ling XIAO
;
Hong YU
;
Hua QU
;
Qiaoguang HAO
;
Shouwu XIANG
;
Xia LI
;
- Publication Type:Journal Article
- Keywords:
Poststroke depression and anxiety;
Paroxetine;
psychotherapy
- From:
Chinese Mental Health Journal
2002;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the efficacy of paroxetine and psychotherapy in patients with poststroke de- pression and anxiety.Methods:81 patients who met the CCMD-3 criteria of depression and anxiety after acute brain stroke were recruited and randomized into 3 groups.Group A was treated with routine antistroke medication and paroxetine;Group B was treated with routine antistroke medications,paroxetine plus psychotherapy;Group C(con- trol)was treated with routine antistroke medication.All patients were treated for 6 weeks and evaluated with SSS, HAMD,HAMA as measures of efficacy and side effects.Results:The comorbidity rate of poststroke depression and anxiety was 65.9%.According to the reduction of SSS,HAMD and HAMA scores,and increase of BI score,signifi- cant improvement has been showed in all patients.There was significant difference among group A,B and the control group(P
