The study on antibacterial activity in vitro of Cefdinir and other four antimicrobial agents against pathogen from community respiratory tract infections
- VernacularTitle:头孢地尼等五种抗菌药物对呼吸道感染致病菌体外抗菌活性的研究
- Author:
Jiao QIAN
;
Dong CHAI
;
Zhuanjie ZHENG
;
Rui WANG
;
- Publication Type:Journal Article
- Keywords:
Cefdinir;
Respiratory tract infections;
Drug resistance,microbial
- From:
Chinese Journal of Laboratory Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the antibacterial activity of Cefdinir compared with other four antimicrobial agents against common isolates in vitro.Methods Minimal lnhibitory Concentrations (MIC) were determined by agar dilution method Results Staphylococcus aureus (MSSA) showed highest susceptibility to Cefdinir with 100% susceptible rate, Streptococcus pneumoniae (including PSSP and PISP) showed higher susceptibility to Cefdinir with 63 6% 100 0% susceptible rate Hemophilus influenza and Moraxelle catarrhalis both showed good susceptibility to three kinds of cephalosporins and Azithromycin Klebsiella pneumoniae (including ESBLs positive strains) were resistant to three kinds of cephalosporins, while ESBLs negative Klebsiella pneumoniae were sensitive to three kinds of cephalosporins, with 73 10%~88 50% susceptible rate Conclusion Compared with other four antimicrobial agents, Cefdinir has a powerful antibacterial activity to pathogen from respiratory tract infections
