A Case of Fatal Scedosporium prolificans Fungemia in a Patient with Acute Myeloid Leukemia.
- Author:
Goeun LEE
1
;
Jeeyong KIM
;
Kyung Hee KIM
;
Jung Ah KWON
;
Yunjung CHO
;
Young Kee KIM
;
Kap No LEE
;
Chang Kyu LEE
Author Information
1. Department of Laboratory Medicine, Korea University, College of Medicine, Seoul, Korea. cklee@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Scedosporium prolificans;
Fungemia;
Immunocompromised
- MeSH:
Drug Therapy;
Female;
Fungemia*;
Fungi;
Humans;
Immunocompromised Host;
Leukemia, Myeloid, Acute*;
Middle Aged;
Recurrence;
Relapsing Fever;
Scedosporium*
- From:Korean Journal of Clinical Microbiology
2005;8(2):194-197
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Scedosporium prolificans is a saprophytic fungus widespread in the environment. It has become an emerging pathogen in recent years causing disseminated infections, especially in profoundly neutropenic immunocompromised patients. We report a case of fatal Scedosporium fungemia in a 45 year old female with acute myeloid leukemia in relapse. She received salvage chemotherapy and antibiotic treatment, and was neutropenic with relapsing fever. S. prolificans was isolated repeatedly from the aerobic bottles on the second day of two successive blood cultures. Amphotercin B was started; however, the patient expired the next day.