The molecular cytologic research progress of Carvedilol on myocardial and vascular injury
- VernacularTitle:卡维地洛防治心肌血管损伤的细胞分子学研究进展
- Author:
Jingrevewing WANG
;
Shi-Sen JIANG
;
- Publication Type:Journal Article
- Keywords:
Carvedilol;
Antioxidant;
Apoptosis;
Proliferation
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Carvedilol is a non-selective beta-blocker with additional blockade of alpha_(1)-adrenoceptors.It has been applied in the treatment of hypertention、stable angina pectoris、chronic heart failure.In addition,Carvedilol exerts antioxidant and anti-apoptosis effects,it can inhibits vascular smooth muscle cell proliferation、migration and neointimal formation following vascular injury.The article makes a review on the molecular cytologic mechanism of Carvedilol in these aspects.