Judgment about myocardial function with plasma BNP in patients with noninsulin-dependent diabetes mellitus
- VernacularTitle:脑钠素在判断2型糖尿病患者心肌舒缩功能的作用研究
- Author:
Yitian CHEN
;
Shisen JIANG
;
Ruiji XU
;
Cheng HUANG
;
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
BNP;
Cardiac function
- From:
Journal of Medical Postgraduates
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the alteration of cardiac function in diabetic patients and evaluate the relationship between cardiac function and BNP. Methods:83 diabetic patients and 12 healthy subjects were selected into the study. Left ventricular ejection fraction(LVEF) and mitral annular early diastole (E) and late diastole (A) inflow velocities were measured with echocardiography. Plasma BNP were measured with Immnoradiometic assay(IRMA)? Results:According to the result of the echocardiography, the diabetics who have no primary cardiac diseases were subdivided into normal cardiac function group( n =24,28.9%),diastolic dysfunction group( n =47,56.7%), systolic dysfunction group( n =6,7.2%), both diastolic and systolic dysfunction group( n =6,7.2%). More than half of diabetic patients have diastolic dysfunction. The plasma level of BNP had significant negative correlation with LVEF( r = -0.614, P
