Clinical role of PET in cancer diagnosis
- VernacularTitle:正电子发射体层摄影在癌症患者中的临床应用
- Author:
Jun-Kun CHEN
;
- Publication Type:Journal Article
- Keywords:
Tumor;
Tomography;
Emission-computed
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Positron emission tomography(PET) is a diagnostic imaging technique for the identification of biochemical and physiologic alterations in tumors. Use of PET performed with 18-fluoro-2-deoxy-2-fluor-D-glucose (FDG) may significantly improve the accuracy of tumor imaging. FDG PET based on identification of fundamental aspects of tumor metabolism has gained widespread acceptance in the initial staging of cancer,cancer recurrence, and monitoring the response to therapy. FDG uptake is proportional to the increasing metabolic rate of glucose demanding of tumor cell. The high sensitivity and high negative predictive value of FDG PET in most of malignant tumors enable this technique to play a greater role in guiding the tumor management at initial staging and follow-up.
