LARGE-SCALE YEAST TWO-HYBRID SYSTEM IN THE APPLICATION ON MAP OF PROTEOME INTERACTOME
- VernacularTitle:大规模的酵母双杂交系统在蛋白质相互作用组图谱中的应用
- Author:
Hai-Rong MA
;
Wei-Qi LI
;
- Publication Type:Journal Article
- Keywords:
Large-scale yeast two-hybrid system, Protein interactome mapping, Array screening, Library screening
- From:
Microbiology
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Protein fulfilling the their roles, one of important ways is through protein-protein interaction. In functional genomic era, identifying all of protein-protein interaction in proteome and mapping the protein interactions that have been attracting many scientists' attention , of which large-scale yeast two-hybrid system is one strategy of most widely used. In recent two years, ambitious projects have launched to examine all of the protein-protein interaction in Saccharomyces cer-evisiae using large-scale yeast two-hybrid system. Nevertheless, huge protein network is larger than that we predict and single yeast two-hybrid system cannot solve all the problems, which need be complemented by other wags.
