Changes of intramucosal pH(pHi) after severe craniocerebral injuries and the correlation to bleeding from stress ulceration
- VernacularTitle:重型颅脑外伤后胃粘膜内pH值的变化及其与应激性溃疡出血的关系
- Author:
Xiaoyu ZHU
;
Jixin SHI
;
- Publication Type:Journal Article
- Keywords:
Craniocerebral injury;
Stress ulceration;
Intramucosal pH;
Tonometry
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the changes of intramucosal pH(pHi) after severe craniocerebral injuries and the correlation to bleeding from stress ulceration. Methods:Nineteen cases of severe head trauma patients were enrolled, their pHi were determined at different time point with tonometry. The pH of gastric juice and plasma gastrin concentrations were monitored for 7 days. Results:Five cases(bleeding group) developed stress ulcer bleeding. On admission, the pHi were not significantly different in the non bleeding group, but the differences between two groups at 12 hours, 24 hours, the 3rd day, the 5th day, the 7th day after admission were significant, pHi in the bleeding group was statistically lower than non bleeding group. The pH values of gastric juice and the plasma gastrin concentrations were not different significantly between two groups during each therapeutic periods. Conclusion:Bleeding group had significantly lower pHi than non bleeding group during the therapeutic periods. pHi was predictive for bleeding from stress ulceration after severe craniocerebral injury.
