Pilot study on measurement of sICAM-1 and sE-selectin in patients with chronic hepatitis C to judge response to treatment
- VernacularTitle:可溶性细胞间粘附分子-1和E-选择素水平在判断干扰素-?2b治疗慢性丙型肝炎疗效的初步研究
- Author:
Jing TENG
;
Wenhao CHEN
;
Wenhong XU
;
Yanshan HONG
;
- Publication Type:Journal Article
- Keywords:
Inter cellular adhesion molecules 1;
E selectin;
Hepatitis C, chronic
- From:
Chinese Journal of Laboratory Medicine
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of sICAM 1 and sE selectin in patients with chronic hepatitis(CHC) and to study their roles in judge of response to IFN ? 2b treatment. Methods sICAM 1 and sE selectin levels were measured in 32 cases of CHC before and after treatment of IFN ? 2b by enzyme linked immunosorbent assay(ELISA), levels of HCV RNA was detected by quantitative PCR and serum ALT activity was also detected. Results Levels of sICAM 1 and sE selectin in CHC patients were significantly higher than those in normal controls(P
