To study on the relation between clinical character and telomerase in oral squamous cell carcinoma
- VernacularTitle:口腔鳞状细胞癌临床特征与端粒酶相关性研究
- Author:
Zhihong ZHANG
;
Maochang YE
;
Chuanjun CHEN
;
Haiming DAI
;
Jin WU
;
Jing CHENG
;
- Publication Type:Journal Article
- Keywords:
Telomerase;
Mouth mucosa;
Squamous cell carcinoma;
Lymphatic metastasis
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To find out the relation between main clinical character and telomerase activity in oral squamous cell carcinomas. Methods:Telomerase activity was detected by telomerase PCR ELISA assay in 12 cases of oral normal tissue and 45 cases of oral squamous cell carinoma. Results:Telomerase activity was not detectable in 12 cases of oral normal tissue. Telomerase activity was detected in 75.67 percent of oral squamous cell carcinomas. Telomerase activity was present more frequently in advanced oral squamous cell carinoma than in the early stage( P