Clinical Study of Matrix Metalloproteinase-9 and transforming growth factor-?_1 related with diabetic nephropathy
- VernacularTitle:血清基质金属蛋白酶-9及转化生长因子?_1与糖尿病肾病的关系
- Author:
Zhimin DING
;
Jianxin WU
;
Yuanyuan LI
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinase 9;
Transforming growth factor ?1;
Diabetic nephropathy
- From:
Chinese Journal of Diabetes
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study whether serum matrix metalloproteinase 9, serum transforming growth factor ? 1, serum type C IV collagen concentrations are alternatoin in various stages of patients with T2DM. Methods 64 cases T2DM patients were divided into three groups according to urine albumin excretion rate (UAER):normoalbuminuria (NA)group and microalbuminuria (MA) group and overt diabetic nephropathy (ODN)group. Serum MMP 9,TGF ? 1 and C IV were detected in all cases. Results Serum MMP 9 in MA and ODN groups were higher than NA and normal control groups ( P
