Effects of peripheral nervous system on fracture healing
- VernacularTitle:周围神经系统对骨折愈合影响的实验研究
- Author:
Qun XIA
;
Jun MIAO
;
Jidong ZHANG
;
Hongbin JIN
;
- Publication Type:Journal Article
- Keywords:
Fracture healing;
Nerve;
Biomechanics;
Bone histomorphometry
- From:
Chinese Journal of Orthopaedic Trauma
2002;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of peripheral nervous system on early and middle periods of fracture healing. Methods Denervated tibia fracture model and innervated tibia fracture model were made at the same rat. The animals were executed at day 15 and day 30 after operation respectively. Callus sizes were evaluated by radiograph. The mechanical properties of calluses were recorded in a three point bending test. The callus microstructures were measured by bone histomorphometry.Results Radiograph showed an increased callus formation in the denervated group both on day 15 and day 30 after operation (P0.05). Compared with the innervated groups, 30 days dynamic parameters indicated that mineral appositional rates of the denervated sides significantly decreased (P
