Effects of Repeated Immobilization Stress on the Renal Peripheral Benzodiazepine Receptor in Rats.
- Author:
Yong Hoon PARK
;
Han Ku MOON
;
Son Moon SHIN
;
Eun Ju LEE
;
Eun Sil LEE
;
Jeoung Hee HA
- Publication Type:Original Article
- Keywords:
Fine needle aspiration cytology;
Mixed squamous cell carcinoma and papillary carcinoma;
Thyroid gland
- MeSH:
Aged;
Animals;
Benzodiazepines*;
Biopsy, Fine-Needle;
Carcinoma, Small Cell;
Chromatin;
Female;
Fungi;
Humans;
Immobilization*;
Immunohistochemistry;
Lymphocytes;
Parotid Gland;
Rats*;
Receptors, GABA-A*;
Salivary Glands;
Thyroid Gland
- From:Journal of the Korean Society of Pediatric Nephrology
1999;3(1):20-26
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary small cell carcinoma of the salivary gland is a rare neoplasm that accounts for approximately 1.8% of all primary major salivary gland malignancies. Because of its rarity, it is difficult to diagnose small cell carcinoma of the parotid gland by fine needle aspiration cytology(FNAC). We experienced a case of primary small cell carcinoma of the parotid gland in a 72-year-old woman who presented with two palpable masses of the left infraauricular and ocular regions of two to three month's duration, respectively. Aspirate smears from the left infraauricular area were highly cellular on necrotic and lymphocytic background and showed individually dispersed cells or three-dimensional clusters of small cells. The tumor cells were round to oval with a very high nucleocytoplasmic ratio. Nuclei were about two times the size of lymphocytes and had uniformly dispersed but hyperchromatic to pyknotic chromatin. Nucleoli were occasionally visible but were generally inconspicuous. Numerous mitotic figures were detected. The clusters of these small tumor cells exhibited angular nuclear molding, irregular nuclear outlines, and occasionally rosette like arrangement. The tumor was confirmed by histology and immunohistochemistry.
